he Tiber River cuts through Rome in the shape of a serpent, splitting the ancient city in half.

On one side is the Vatican, home to the Catholic Church with the large dome of St. Peter’s Basilica looming over the city’s skyline. Directly across from the Vatican is Palazzo Montecitorio, seat of the Italian parliament. It is a place many Italians despise because it houses bickering politicians.

These two forces, within miles of each other, yet far apart in so many other ways, could come into renewed conflict over the coming weeks.

Italy’s government was plunged into chaos this past Tuesday when the nationalist-populist coalition that had struck fear across the European establishment fell apart. It means that Italians could be going to the ballot box once again in late October. It’s also a sign of how powerful the Catholic Church remains, mostly behind the scenes, in helping to determine the country’s political outcomes.

Matteo Salvini, leader of the right-wing party known as The League, triggered the political tsunami after he abandoned the anti-establishment Five Star Movement in an effort to force a no-confidence vote and provoke new elections. Ahead of the vote, Prime Minister Giuseppe Conte announced that he was resigning, which officially brought the coalition to its knees.

The developments of the past week have left a power vacuum that will be filled either in the upcoming elections or if the Five Star Movement creates a ruling coalition with the center-left Democratic Party and several other smaller political factions. Salvini, who had served as the country’s interior minister and deputy prime minister, is pushing for a vote.

Salvini’s 40% approval rating — considered high for a country known for its very fractured political system — could very well get him elected prime minister. At the same time, traditional conservatives, led by billionaire-turned-politician Silvio Berlusconi and his Forza Italia party, have seen support eroded as voters increasingly flock to the League.

That these political parties, largely rejected by the electorate last year, want to join forces and stop the anti-immigrant League should come as no surprise. Undoubtedly, the Catholic Church will be rooting for such an outcome, favoring a French-style centrist coalition.

After elections gave right-wing populists sweeping victories in the Catholic nations of Italy, Poland and France in the European elections, it seemed clear that the biggest loser wasn’t the political left or moderate political parties.

The side that suffered the biggest defeat was Pope Francis.

In Italy, The League party snagged 33 percent of the vote, a remarkable achievement given the country’s fragmented political system. The pro-European Democratic Party could only muster 22 percent of the vote, while the left-wing populist Five Star Movement finished third at 18 percent. The League victory highlighted the divisions within Roman Catholicism. Party leader Matteo Salvini — known for his nationalistic and anti-immigration rhetoric — didn’t shy away from his faith. On the contrary, he used church symbols to win seats.

It isn’t the first time in European history that the Catholic church, and the papacy, has been viewed with disdain. Over the past few years, the political populism that has enveloped Europe has sought to blame much of its social and economic misfortune on elites. While many of these elites traditionally hail from the political left, the doctrinal left — and with it the current Vatican hierarchy headed by Pope Francis — has also become a target in recent elections.

The election results capped off a bad week for the pontiff. While having to deal with populism undercutting Catholic social teaching, Pope Francis denied he knew about former Cardinal Theodore McCarrick’s history of sexual misconduct with seminarians in an interview with Mexican TV network Televisa. The scandal has plagued the papacy since last summer.

The European election, contested every five years, firmly places populism among the continent’s most powerful political forces. Never shy about brandishing a rosary or invoking God’s help, Salvini has provided Italians with an alternative to the pro-migrant stance and the church’s traditional social teachings put forth by the pope.

“I thank the man up there — with no exploitations,” Salvini told reporters, while kissing a rosary he was clutching in his hand, as results came in on May 26.